Invention Grant
- Patent Title: Modulators of PCSK9 expression
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Application No.: US16671630Application Date: 2019-11-01
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Publication No.: US11000595B2Publication Date: 2021-05-11
- Inventor: Eric E. Swayze , Susan M. Freier , Huynh-Hoa Bui
- Applicant: Ionis Pharmaceuticals, Inc.
- Applicant Address: US CA Carlsbad
- Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/04 ; A61K47/54 ; A61K31/7125 ; A61K31/712 ; A61K9/00 ; A61K47/68 ; A61P3/06 ; A61K31/7115 ; C12N15/113

Abstract:
The present embodiments provide methods, compounds, and compositions useful for inhibiting PCSK9 expression, which may be useful for treating, preventing, or ameliorating a disease associated with PCSK9.
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