Provided is a workpiece retention device that retains a frame which includes a workpiece main body and a lip flange and a base flange that are provided to the workpiece main body, wherein: the workpiece retention device comprises a plurality of grippers that are aligned in the lengthwise direction of the frame, and a horizontal movement mechanism and a vertical movement mechanism that move the plurality of grippers; the gripper each include: a lower block, a workpiece support pin that is provided to the lower block and that supports the frame, an upper block that can move toward the base flange of the supported frame, a block movement mechanism that moves the upper block; and a suction mechanism that is provided to the upper block and that suctions the workpiece main body on the base flange side.