Invention Grant
- Patent Title: 2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ROR1 activity
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Application No.: US16314708Application Date: 2017-07-10
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Publication No.: US11008318B2Publication Date: 2021-05-18
- Inventor: Håkan Mellstedt , Styrbjörn Byström , Jan Vågberg , Elisabeth Olsson
- Applicant: KANCERA AB
- Applicant Address: SE Solna
- Assignee: KANCERA AB
- Current Assignee: KANCERA AB
- Current Assignee Address: SE Solna
- Agency: Renner, Otto, Boisselle & Sklar, LLP
- Priority: EP16178928 20160711
- International Application: PCT/EP2017/067262 WO 20170710
- International Announcement: WO2018/011138 WO 20180118
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P25/28
![2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ROR1 activity](/abs-image/US/2021/05/18/US11008318B2/abs.jpg.150x150.jpg)
Abstract:
Compound of formula (I′) or (I″) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of mammalian kinase enzyme activity, including ROR1 tyrosine kinase activity and may be used in the treatment of disorders associated with such activity.
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