Invention Grant
- Patent Title: Pharmaceutical composition for preventing or treating aging-related diseases containing decursin derivative as active ingredient
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Application No.: US16605802Application Date: 2018-04-25
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Publication No.: US11008332B2Publication Date: 2021-05-18
- Inventor: Bum Joon Park , Gyu Yong Song , Yu Seok O , Jee Hyun Lee , Eun Ju Yun
- Applicant: PRG S&TECH INC.
- Applicant Address: KR Busan
- Assignee: PRG S&TECH INC.
- Current Assignee: PRG S&TECH INC.
- Current Assignee Address: KR Busan
- Agency: Revolution IP, PLLC
- Priority: KR10-2017-0052787 20170425,KR10-2018-0045593 20180419
- International Application: PCT/KR2018/004812 WO 20180425
- International Announcement: WO2018/199633 WO 20181101
- Main IPC: A61P43/00
- IPC: A61P43/00 ; A61P17/00 ; C07D493/04 ; A61K45/06
Abstract:
A composition for preventing or treating an aging-related disease includes a novel decursin derivative as an active ingredient, wherein the novel decursin derivative has exhibited an excellent effect of inhibiting progerin expression and excellent effect of inhibiting binding between progerin and lamin A, and it has been confirmed that the novel decursin derivative prolongs the survival period of animal models in which progerin was induced.
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