Invention Grant
- Patent Title: Designer osteogenic proteins
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Application No.: US16211493Application Date: 2018-12-06
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Publication No.: US11008373B2Publication Date: 2021-05-18
- Inventor: Stephen Berasi , Robert Vincent Martinez , Michael John Cain , John Martin Wozney , Howard Seeherman , Zong Sean Juo , Valerie Perrine Calabro , Christopher Todd Brown
- Applicant: Wyeth LLC
- Applicant Address: US NY New York
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NY New York
- Agency: Kacvinsky Daisak Bluni, PLLC
- Main IPC: C07K14/51
- IPC: C07K14/51 ; C12N15/63 ; C12N5/10 ; A61K38/16 ; A61K38/18
Abstract:
The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
Public/Granted literature
- US20190241634A1 DESIGNER OSTEOGENIC PROTEINS Public/Granted day:2019-08-08
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