Invention Grant
- Patent Title: In vitro model for a tumor microenvironment
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Application No.: US16282815Application Date: 2019-02-22
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Publication No.: US11008549B2Publication Date: 2021-05-18
- Inventor: Brian R. Wamhoff , Brett R. Blackman , Robert A. Figler , Daniel G. Gioeli , Michael B. Simmers
- Applicant: HemoShear, LLC
- Applicant Address: US VA Charlottesville
- Assignee: HemoShear, LLC
- Current Assignee: HemoShear, LLC
- Current Assignee Address: US VA Charlottesville
- Agency: Stinson LLP
- Main IPC: C12N5/09
- IPC: C12N5/09 ; C12N5/071
Abstract:
Methods for mimicking a tumor microenvironment in vitro are provided. The methods comprise indirectly applying a shear stress upon at least one tumor cell type plated on a surface within a cell culture container. Methods for mimicking tumor metastasis and methods for testing drugs or compounds in such systems are also provided.
Public/Granted literature
- US20200010809A1 IN VITRO MODEL FOR A TUMOR MICROENVIRONMENT Public/Granted day:2020-01-09
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