Invention Grant
- Patent Title: 3′ end caps for RNAi agents for use in RNA interference
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Application No.: US16249128Application Date: 2019-01-16
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Publication No.: US11008570B2Publication Date: 2021-05-18
- Inventor: Jeremy Lee Baryza , Marcel Blommers , Cesar Fernandez , Erin Geno , Alvar Gossert , Paulette Greenidge , Dieter Huesken , Juerg Hunziker , Francois Jean-Charles Natt , Anup Patnaik , Andrew Patterson , Jean-Michel Rene Rondeau , Jan Weiler , Meicheng Zhu
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Brinks Gilson & Lione
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C12N15/11 ; C07D215/12 ; C07D215/14 ; C07D311/80 ; C07C69/40 ; C07D217/14 ; C07D401/04 ; C07D213/30 ; C07C43/23 ; C07C233/01 ; C07D217/16 ; C07D217/18
Abstract:
The disclosure relates to novel compounds and compositions comprising a RNAi agent comprising a novel compound as a 3′ end cap. The disclosure also relates to processes for making such compositions, and methods and uses of such compositions, e.g., to mediate RNA interference.
Public/Granted literature
- US20190390196A1 3'END CAPS FOR RNAi AGENTS FOR USE IN RNA INTERFERENCE Public/Granted day:2019-12-26
Information query
IPC分类:
