Invention Grant
- Patent Title: Process for the preparation of triple-bond-containing optically active carboxylic acids, carboxylate salts and carboxylic acid derivatives
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Application No.: US16087402Application Date: 2017-03-21
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Publication No.: US11008594B2Publication Date: 2021-05-18
- Inventor: Irén Hortobágyi , István Lászlófi , Zsuzsanna Kardos , József Molnár , László Takács , Tamás Bán
- Applicant: CHINOIN GYÓGYSZER ÉS VEGYÉSZETI TERMÉKEK GYÁRA ZRT.
- Applicant Address: HU Budapest
- Assignee: CHINOIN GYÓGYSZER ÉS VEGYÉSZETI TERMÉKEK GYÁRA ZRT.
- Current Assignee: CHINOIN GYÓGYSZER ÉS VEGYÉSZETI TERMÉKEK GYÁRA ZRT.
- Current Assignee Address: HU Budapest
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: HUP1600204 20160322
- International Application: PCT/EP2017/056689 WO 20170321
- International Announcement: WO2017/162667 WO 20170928
- Main IPC: C12P7/62
- IPC: C12P7/62 ; C07F9/40 ; C12P7/40 ; C12P41/00 ; C07C57/18 ; C07C69/24
Abstract:
The invention provides a new enzimatic process for the preparation of chiral carboxylic acids, their salts and acid derivatives of the general formula (I) by enzymatic hydrolysis of racemic carboxylic acid ester of the general formula (II) and optionally subsequent esterification or acylation.
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