Centralized communication server systems and methods are provided. In one embodiment, a centralized server includes at least one network interface for bidirectional communication with mobile devices. At least one processor is configured to receive, via the computer network, event information for a discharge event associated with an individual, automatically identify a department associated with the one or more rooms, automatically receive protocol information for the identified department, and identify one or more milestones. The processor(s) are further configured to automatically generate workload data based on the identified milestones, receive assignment information for a plurality of individuals associated with the protocol information, and automatically assign the one or more milestones to the first individual. The processor(s) are further configured to automatically generate a first electronic notification addressed to the first mobile device, including information associated with the at least one discharge event and the one or more milestones.