An endoscopic surgical device that includes: a sheath; a manipulator; a manipulation wire; a clip body having a pair of arms, connected to a distal end of the manipulation wire, and configured to be capable of advancing and retracting in accordance with manipulation of the manipulator along with a longitudinal axis of the manipulation wire; a holding tube into which a proximal portion of the clip body is inserted to be capable of advancing and retracting; and a biasing member configured to hold a position of the manipulation wire at an initial position. The clip body is nonrotatable around the longitudinal axis at the initial position. When the manipulation wire is advanced a prescribed amount against a biasing force of the biasing member, the clip body is rotatable around the longitudinal axis, and is allowed adjustment of an opening-closing direction of the pair of arms.