- Patent Title: Compounds, compositions and methods for treating insulin resistance
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Application No.: US16496111Application Date: 2018-03-20
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Publication No.: US11020378B2Publication Date: 2021-06-01
- Inventor: Maria Miteva , Bruno Villoutreix , David J. Aitken , Anne-Françoise Burnol , Anais Gondoin , Tarik Issad
- Applicant: UNIVERSITE PARIS DESCARTES , UNIVERSITÉ PARIS-SUD 11 , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE , UNIVERSITE PARIS DIDEROT , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Applicant Address: FR Paris; FR Orsay; FR Paris; FR Paris; FR Paris
- Assignee: UNIVERSITE PARIS DESCARTES,UNIVERSITÉ PARIS-SUD 11,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE,UNIVERSITE PARIS DIDEROT,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee: UNIVERSITE PARIS DESCARTES,UNIVERSITÉ PARIS-SUD 11,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE,UNIVERSITE PARIS DIDEROT,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee Address: FR Paris; FR Orsay; FR Paris; FR Paris; FR Paris
- Agency: Pearne & Gordon LLP
- Priority: FR1752287 20170320
- International Application: PCT/EP2018/056931 WO 20180320
- International Announcement: WO2018/172306 WO 20180927
- Main IPC: A61K31/422
- IPC: A61K31/422 ; A61P3/10 ; A61K31/341 ; A61K31/42 ; A61K31/513

Abstract:
The invention relates to a compound inhibiting the interaction between a Grb14 protein and an insulin receptor of Formula (I) or Formula (II), their salts, solvates, and/or diastereoisomers, for use for therapeutic purposes, in particular for the treatment of insulin resistance, and to pharmaceutical compositions containing such compounds.
Public/Granted literature
- US20200030297A1 NOVEL COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING INSULIN RESISTANCE Public/Granted day:2020-01-30
Information query
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