Invention Grant
- Patent Title: Amino-pyrrolopyrimidinone compounds and methods of use thereof
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Application No.: US15683913Application Date: 2017-08-23
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Publication No.: US11020398B2Publication Date: 2021-06-01
- Inventor: Craig Bates , Sudharshan Eathiraj , Hiroaki Inagaki , Jean-Marc Lapierre , Takayuki Momose , Kiyoshi Nakayama , Takashi Odagiri , Masahiro Ota , Yusuke Ota , Yoshihiro Shibata , Manish Tandon , Tomoyuki Tsunemi
- Applicant: ArQule, Inc.
- Applicant Address: US MA Burlington
- Assignee: ArQule, Inc.
- Current Assignee: ArQule, Inc.
- Current Assignee Address: US MA Burlington
- Agency: Cooley LLP
- Agent Matthew Pavao; Chen Chen
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61K31/4188 ; C12N9/12 ; A61K31/03 ; A61K31/341 ; A61P9/00 ; A61P7/04 ; A61P43/00 ; A61P37/08 ; A61P37/00 ; A61P37/06 ; A61P35/02 ; A61P35/00 ; A61P29/00 ; A61P25/00 ; A61P19/02 ; A61P17/00 ; A61P11/06 ; A61P1/04

Abstract:
The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of BTK, a pharmaceutical composition comprising a compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.
Public/Granted literature
- US20180055846A1 AMINO-PYRROLOPYRIMIDINONE COMPOUNDS AND METHODS OF USE THEREOF Public/Granted day:2018-03-01
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