Invention Grant
![Process for the preparation of freeze-dried 2-[(3-aminopropyl)amino] ethanethiol formulation](/docs/US/2021-06-01/US11021442B2/abs.jpg.600x600.jpg)
- Patent Title: Process for the preparation of freeze-dried 2-[(3-aminopropyl)amino] ethanethiol formulation
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Application No.: US16465505Application Date: 2017-11-29
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Publication No.: US11021442B2Publication Date: 2021-06-01
- Inventor: Xiuping Wang-Zhang , Perrine Pivette , Karine Gonzalez , Eric Deutsch , Céline Clemenson
- Applicant: CLEVEXEL PHARMA , INSTITUT GUSTAVE ROUSSY
- Applicant Address: FR Paris; FR Villejuif
- Assignee: CLEVEXEL PHARMA,INSTITUT GUSTAVE ROUSSY
- Current Assignee: CLEVEXEL PHARMA,INSTITUT GUSTAVE ROUSSY
- Current Assignee Address: FR Paris; FR Villejuif
- Agency: Oliff PLC
- Priority: EP16306582 20161130
- International Application: PCT/EP2017/080881 WO 20171129
- International Announcement: WO2018/100008 WO 20180607
- Main IPC: C07C323/25
- IPC: C07C323/25 ; A61P17/02 ; A61K9/06 ; A61K9/19
![Process for the preparation of freeze-dried 2-[(3-aminopropyl)amino] ethanethiol formulation](/abs-image/US/2021/06/01/US11021442B2/abs.jpg.150x150.jpg)
Abstract:
A process for the preparation of freeze-dried 2-[(3-aminopropyl)amino]ethanethiol including the following steps: a) the reaction of a solution of amifostine with a strong acid, to obtain a solution of 2-[(3-aminopropyl)amino]ethanethiol, and b) the freeze-drying of the solution of 2-[(3-aminopropyl)amino]ethanethiol, with or without addition of excipients.
Public/Granted literature
- US20200239414A1 PROCESS FOR THE PREPARATION OF FREEZE-DRIED 2-[(3-AMINOPROPYL)AMINO]ETHANETHIOL FORMULATION Public/Granted day:2020-07-30
Information query
