Invention Grant
- Patent Title: Compositions and methods for modulating farnesoid X receptors
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Application No.: US16854762Application Date: 2020-04-21
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Publication No.: US11021446B2Publication Date: 2021-06-01
- Inventor: Donatella Chianelli , Runyan Li , Valentina Molteni , John Nelson , Jason Thomas Roland , Paul Vincent Rucker , David Charles Tully , Xiaoyang Wang , Liladhar Murlidhar Waykole , Yubo Zhang , Bo Zhou
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agency: Novartis Institues for BioMedical Reseach, Inc.
- Agent Emily T Wu
- Main IPC: C07D231/54
- IPC: C07D231/54 ; C07D471/04 ; C07D491/052 ; A61K31/416 ; A61K31/4162 ; A61K31/4439 ; A61K31/4745 ; C07D471/06

Abstract:
The present invention relates to compounds of Formula I, a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X receptors (FXR).
Public/Granted literature
- US20200247757A1 COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS Public/Granted day:2020-08-06
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