Invention Grant
- Patent Title: Artificial catalyst system for selective acylation of chromosome protein
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Application No.: US15755938Application Date: 2016-08-29
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Publication No.: US11021461B2Publication Date: 2021-06-01
- Inventor: Motomu Kanai , Shigehiro Kawashima , Kenzo Yamatsugu , Yoshifumi Amamoto , Yuki Aoi , Hiroki Suto , Nozomu Nagashima , Hitoshi Kurumizaka , Akihisa Osakabe , Yasuhiro Arimura
- Applicant: THE UNIVERSITY OF TOKYO
- Applicant Address: JP Tokyo
- Assignee: THE UNIVERSITY OF TOKYO
- Current Assignee: THE UNIVERSITY OF TOKYO
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JPJP2015-169448 20150828
- International Application: PCT/JP2016/075183 WO 20160829
- International Announcement: WO2017/038760 WO 20170309
- Main IPC: A61P35/00
- IPC: A61P35/00 ; C07D401/14 ; C07K1/13 ; A61K45/06 ; A61K31/4439 ; A61K31/16
Abstract:
An artificial catalyst system which can acylate chromosome proteins with high selectivity has successfully been established by using a combination of an acyl CoA activating catalyst having target acylation area binding ability and acyl CoA or a derivative thereof.
Public/Granted literature
- US20190047985A1 ARTIFICIAL CATALYST SYSTEM FOR SELECTIVE ACYLATION OF CHROMOSOME PROTEIN Public/Granted day:2019-02-14
Information query
IPC分类:
| A | 人类生活必需 |
| A61 | 医学或兽医学；卫生学 |
| A61P | 化合物或药物制剂的特定治疗活性 |
| A61P35/00 | 抗肿瘤药 |
