Invention Grant
- Patent Title: DNA-PK inhibitors
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Application No.: US16654084Application Date: 2019-10-16
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Publication No.: US11021465B2Publication Date: 2021-06-01
- Inventor: Paul S. Charifson , Kevin Michael Cottrell , Hongbo Deng , John P. Duffy , Huai Gao , Simon Giroux , Jeremy Green , Katrina Lee Jackson , Joseph M. Kennedy , David J. Lauffer , Mark Willem Ledeboer , Pan Li , John Patrick Maxwell , Mark A. Morris , Albert Charles Pierce , Nathan D. Waal , Jinwang Xu
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Dechert LLP
- Agent Andrea L. C. Reid; Danielle M. Nihan
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D401/04 ; C07D403/04 ; C07D403/10 ; C07D409/04 ; C07D409/14 ; C07D413/04 ; C07D413/10 ; C07D417/04 ; C07D417/14 ; C07D471/04 ; C07D491/048 ; C07D491/056 ; C07D495/04 ; C07D521/00 ; C07D239/42 ; C07D417/10 ; A61K9/20 ; A61K9/48 ; A61K31/506 ; A61K31/5377 ; A61K47/55 ; A61K47/54 ; A61K31/53 ; C07D401/12 ; C07D403/12 ; C07D403/14 ; A61K41/00
Abstract:
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
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