Invention Grant
- Patent Title: Coumarin-like cyclic compound as MEK inhibitor and use thereof
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Application No.: US16625258Application Date: 2018-06-22
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Publication No.: US11021486B2Publication Date: 2021-06-01
- Inventor: Qinghua Mao , Chengde Wu , Yong Huang , Zhen Gong , Jian Li , Shuhui Chen
- Applicant: CSTONE PHARMACEUTICALS , CSTONE PHARMACEUTICALS (SUZHOU) CO., LTD. , CSTONE PHARMACEUTICALS (SHANGHAI) CO., LTD.
- Applicant Address: KY Grand Cayman; CN Jiangsu; CN Shanghai
- Assignee: CSTONE PHARMACEUTICALS,CSTONE PHARMACEUTICALS (SUZHOU) CO., LTD.,CSTONE PHARMACEUTICALS (SHANGHAI) CO., LTD.
- Current Assignee: CSTONE PHARMACEUTICALS,CSTONE PHARMACEUTICALS (SUZHOU) CO., LTD.,CSTONE PHARMACEUTICALS (SHANGHAI) CO., LTD.
- Current Assignee Address: KY Grand Cayman; CN Jiangsu; CN Shanghai
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: CN201710488401.X 20170623,CN201810596587.5 20180611
- International Application: PCT/CN2018/092457 WO 20180622
- International Announcement: WO2018/233696 WO 20181227
- Main IPC: C07D491/052
- IPC: C07D491/052 ; A61P35/00
Abstract:
Disclosed are a class of coumarin-like cyclic compounds as MEK inhibitors and pharmaceutical compositions comprising the compounds, and the use of same in the preparation of a drug for treating MEK-related diseases. Particularly disclosed are compounds as shown in formula (I) and pharmaceutically acceptable salts thereof or tautomers thereof.
Public/Granted literature
- US20200148695A1 COUMARIN-LIKE CYCLIC COMPOUND AS MEK INHIBITOR AND USE THEREOF Public/Granted day:2020-05-14
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