Invention Grant
- Patent Title: Transforming growth factor beta receptor type II fusion polypeptides
-
Application No.: US15969957Application Date: 2018-05-03
-
Publication No.: US11021527B2Publication Date: 2021-06-01
- Inventor: Ravindra Kumar , Dianne S. Sako
- Applicant: Acceleron Pharma Inc.
- Applicant Address: US MA Cambridge
- Assignee: Acceleron Pharma Inc.
- Current Assignee: Acceleron Pharma Inc.
- Current Assignee Address: US MA Cambridge
- Agency: White & Case LLP
- Main IPC: C07K14/71
- IPC: C07K14/71 ; A61K38/00
Abstract:
In certain aspects, the present disclosure relates to TβRII fusion polypeptides comprising a heterologous portion and a truncated, ligand-binding portion of the extracellular domain of TβRII polypeptide useful to selectively antagonize a TβRII ligand. The disclosure further provides compositions and methods for use in treating or preventing TGFβ associated disorders.
Public/Granted literature
- US20180327477A1 TGF-BETA RECEPTOR TYPE II FUSION PROTEINS AND USES THEREOF Public/Granted day:2018-11-15
Information query
