Invention Grant
- Patent Title: Dock derived compound against laminin receptor (37 LR) and uses thereof
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Application No.: US16555486Application Date: 2019-08-29
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Publication No.: US11022604B2Publication Date: 2021-06-01
- Inventor: Marxa L. Figueiredo , Charles Samuel Umbaugh , Herman O. Sintim , Adriana Diaz-Quinones
- Applicant: Purdue Research Foundation
- Applicant Address: US IN West Lafayette
- Assignee: Purdue Research Foundation
- Current Assignee: Purdue Research Foundation
- Current Assignee Address: US IN West Lafayette
- Agency: Purdue Research Foundation
- Agent Liang Zeng Yan
- Main IPC: G01N33/50
- IPC: G01N33/50 ; G01N33/574 ; G16B15/30 ; G16C20/60 ; G16C20/50 ; A61K31/497
Abstract:
An in silico screening method generated compounds that are against laminin receptor 37LR and their anti-cancer functions in prostate cancer cell lines are disclosed herein. A group of derivatives based on the hit compound from the in silico screening are synthesized and tested with improved IC50 value that can have relevant clinical use for prostate cancer or osteoarthritis.
Public/Granted literature
- US20200064334A1 Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof Public/Granted day:2020-02-27
Information query
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