Invention Grant
- Patent Title: PCI method for generating immune respose to antigenic molecule using checkpoint inhibitor and TLR3 ligand
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Application No.: US15555205Application Date: 2016-03-04
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Publication No.: US11027017B2Publication Date: 2021-06-08
- Inventor: Anders Høgset
- Applicant: PCI Biotech AS
- Applicant Address: NO Oslo
- Assignee: PCI Biotech AS
- Current Assignee: PCI Biotech AS
- Current Assignee Address: NO Oslo
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: GB1503776.5 20150305
- International Application: PCT/EP2016/054714 WO 20160304
- International Announcement: WO2016/139362 WO 20160909
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C12N5/09 ; A61N5/06 ; A61K41/00 ; A61K39/12 ; A61K39/39 ; A61K47/69 ; A61K39/395 ; C07K16/28 ; A61K9/00 ; A61K31/713 ; A61K35/17 ; C12N5/0784 ; C12N5/0786 ; C12N7/00 ; C12N13/00
Abstract:
The invention concerns a method of generating an immune response in a subject, comprising administering to the subject an antigenic molecule, a photosensitizing agent, a checkpoint inhibitor, and irradiating said subject with light of a wavelength effective to activate the photosensitizing agent to generate an immune response. Preferably the method is a method of vaccination. The invention also provides related methods, compositions, cells, uses, products and kits.
Public/Granted literature
- US20180050105A1 METHOD Public/Granted day:2018-02-22
Information query
