Invention Grant
- Patent Title: Itraconazole analogs and use thereof
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Application No.: US16152008Application Date: 2018-10-04
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Publication No.: US11028078B2Publication Date: 2021-06-08
- Inventor: Jun O. Liu , Yingjun Li , Kalyan Kumar Pasunooti , Wukun Liu , Wei Shi , Ruojing Li , Sarah Head
- Applicant: The Johns Hopkins University
- Applicant Address: US MD Baltimore
- Assignee: The Johns Hopkins University
- Current Assignee: The Johns Hopkins University
- Current Assignee Address: US MD Baltimore
- Agency: DLA Piper LLP (US)
- Main IPC: C07D405/14
- IPC: C07D405/14 ; A61K31/496 ; A61K31/506
Abstract:
Provided herein are Itraconazole analogs. Also provided herein are methods of inhibition of Hedgehog pathway, vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, angiogenesis and treatment of disease with Itraconazole analogs.
Public/Granted literature
- US20190040046A1 ITRACONAZOLE ANALOGS AND USE THEREOF Public/Granted day:2019-02-07
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