Invention Grant
- Patent Title: Tricyclic P2-ligand containing potent HIV-protease inhibitors against HIV/AIDS
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Application No.: US16348558Application Date: 2017-11-09
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Publication No.: US11028096B2Publication Date: 2021-06-08
- Inventor: Arun K. Ghosh , Hiroaki Mitsuya , Prasanth Reddy Nyalapatla
- Applicant: PURDUE RESEARCH FOUNDATION
- Applicant Address: US IN West Lafayette
- Assignee: PURDUE RESEARCH FOUNDATION
- Current Assignee: PURDUE RESEARCH FOUNDATION
- Current Assignee Address: US IN West Lafayette
- Agency: Schwegman Lundberg & Woessner, P.A.
- International Application: PCT/US2017/060840 WO 20171109
- International Announcement: WO2018/089621 WO 20180517
- Main IPC: C07D493/06
- IPC: C07D493/06 ; C07D311/78
Abstract:
Various embodiments relate to a compound of the formula (I) and (II), wherein X, X1, X2, X3, and R1-R4 are defined herein, as well as pharmaceutical compositions comprising compounds of the formula (I) and/or (II) and methods of treating an HIV infection comprising administering a therapeutically effective amount of one or more compounds of formula (I) and/or (II), or a pharmaceutical composition comprising compounds of the formula (I) and/or (II), to a patient in need thereof.
Information query
