Invention Grant
- Patent Title: NRF2 activators
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Application No.: US16469203Application Date: 2017-12-11
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Publication No.: US11028099B2Publication Date: 2021-06-08
- Inventor: Carl A. Brooks , Jay M. Matthews
- Applicant: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
- Applicant Address: GB Middlesex
- Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
- Current Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
- Current Assignee Address: GB Middlesex
- Agent Nora L. Stein; Fang Qian; Duke M. Fitch
- International Application: PCT/IB2017/057804 WO 20171211
- International Announcement: WO2018/109646 WO 20180621
- Main IPC: C07D498/04
- IPC: C07D498/04 ; A61K9/00 ; C07C215/12

Abstract:
The present invention relates to a compound which is (R)-3-(1,4-dimethyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-(((R)-2-ethyl-2,3-dihydropyrido[2,3-f][1,4]oxazepin-4(5H)-yl)methyl)-4-methylphenyl)propanoic acid (I), or a pharmaceutically acceptable salt thereof, in particular, the meglumine salt thereof, a pharmaceutical composition containing the compound and its use as an NRF2 activator.
Public/Granted literature
- US20200031846A1 NRF2 ACTIVATORS Public/Granted day:2020-01-30
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