Invention Grant
- Patent Title: Compound for treating metabolic diseases and preparation method and use thereof
-
Application No.: US16626934Application Date: 2018-08-15
-
Publication No.: US11028111B2Publication Date: 2021-06-08
- Inventor: Guoqin Fu , Wei Ding , Bo Yin , Chao Yang , Cuiqin Wang , Yong Dou , Ruiling Wang
- Applicant: Xi' An Biocare Pharma Ltd.
- Applicant Address: CN Shaanxi
- Assignee: Xi' An Biocare Pharma Ltd.
- Current Assignee: Xi' An Biocare Pharma Ltd.
- Current Assignee Address: CN Shaanxi
- Agency: RatnerPrestia
- Priority: CN201711371702.0 20171219
- International Application: PCT/CN2018/100663 WO 20180815
- International Announcement: WO2019/119832 WO 20190627
- Main IPC: C07F9/6574
- IPC: C07F9/6574 ; A61P1/16 ; A61P9/12 ; C07F9/22
Abstract:
Provided are a compound for treating metabolic diseases having the structure as shown in formula (I) or formula (II), or a racemate, stereoisomer, geometric isomer, tautomer, solvate, hydrate, metabolite, pharmaceutically acceptable salt or prodrug thereof. The compound is an activator of FXR and/or a TGR5 receptor, and thus has the activity of activating FXR and/or a TGR5 receptor, and can be used in the preparation of drugs for treating chronic liver diseases, metabolic diseases or portal hypertension.
Information query
