Invention Grant
- Patent Title: Cyphomycin, compositions and uses thereof
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Application No.: US16664722Application Date: 2019-10-25
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Publication No.: US11028113B2Publication Date: 2021-06-08
- Inventor: Timothy S. Bugni , Monica Tallarico Pupo , David R. Andes , Cameron R. Currie , Humberto Enrique Ortega Dominguez
- Applicant: Wisconsin Alumni Research Foundation
- Applicant Address: US WI Madison
- Assignee: Wisconsin Alumni Research Foundation
- Current Assignee: Wisconsin Alumni Research Foundation
- Current Assignee Address: US WI Madison
- Agency: Foley & Lardner LLP
- Main IPC: A61K31/7048
- IPC: A61K31/7048 ; A61K31/351 ; A61K31/4196 ; A61K31/4015 ; A61K31/513 ; C07H17/04 ; C12N1/20
Abstract:
Cyphomycin, an isolated compound of Formula I or IA is provided. A compound isolated from insect Streptomyces and having a chemical formula of C77H122O26 is also provided. Compositions including Cyphomycin, such as pharmaceutical compositions including effective amounts of Cyphomycin for treating fungal infections such as Candida and Aspergillus, including drug-resistant strains thereof, are also disclosed. Methods of treating fungal infections with Cyphomycin and compositions thereof are disclosed.
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