Invention Grant
- Patent Title: Manipulation of genes involved in signal transduction to control fungal morphology during fermentation and production
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Application No.: US16433624Application Date: 2019-06-06
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Publication No.: US11028401B2Publication Date: 2021-06-08
- Inventor: Kenneth S. Bruno , Sachin Jain , Brandon Pfannenstiel , Edyta Szewczyk
- Applicant: Zymergen Inc.
- Applicant Address: US CA Emeryville
- Assignee: Zymergen Inc.
- Current Assignee: Zymergen Inc.
- Current Assignee Address: US CA Emeryville
- Agency: Cooley LLP
- Main IPC: C12N15/80
- IPC: C12N15/80 ; C12N15/90 ; C12R1/865
Abstract:
The present disclosure provides a microbial genomic engineering method and system for transforming, screening, and selecting filamentous fungal cells that have altered morphology and/or growth under specific growth conditions. The method and system utilize high-throughput (HTP) methods to produce filamentous fungal production strains with a desired morphological phenotype.
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