Invention Grant
- Patent Title: Recombinant influenza viruses and constructs and uses thereof
-
Application No.: US13903891Application Date: 2013-05-28
-
Publication No.: US11028408B2Publication Date: 2021-06-08
- Inventor: Daniel R. Perez , Hongjun Chen , Yibin Cai , Lindomar Jose Pena , Matthew Angel
- Applicant: University of Maryland, College Park
- Applicant Address: US MD College Park
- Assignee: University of Maryland, College Park
- Current Assignee: University of Maryland, College Park
- Current Assignee Address: US MD College Park
- Agency: Ballard Spahr LLP
- Main IPC: C12N15/86
- IPC: C12N15/86 ; A61K38/45 ; A61P9/00 ; A61K39/12 ; A61K39/145 ; C12N7/00 ; A61K39/00
Abstract:
Disclosed are compositions and methods comprising one or more recombinant influenza viruses. Recombinant influenza viruses with mutated polymerases and/or rearranged genomes are disclosed. Constructs comprising different influenza nucleic acid sequences are also provided. Methods of inducing protecting immunity with the recombinant influenza viruses are disclosed. Also disclosed are methods of plasmid-free production of influenza virus comprising amplicons comprising one or more of influenza genes.
Public/Granted literature
- US20140161771A1 RECOMBINANT INFLUENZA VIRUSES AND CONSTRUCTS AND USES THEREOF Public/Granted day:2014-06-12
Information query
IPC分类:
