A multi-lens protection device of a mobile phone includes a protector, a multi-lens positioning plate, a first adhesive layer, an opaque printing layer, and a second adhesive layer. The multi-lens positioning plate has at least two perforations corresponding to camera lenses of the mobile phone. The first adhesive layer is attached to one side of the multi-lens positioning plate, facing the protector. The opaque printing layer is attached to one side of the protector, facing the first adhesive layer and adhered to the first adhesive layer. The second adhesive layer is attached to another side of the multi-lens positioning plate, facing away from the first adhesive layer. The perforations of the multi-lens positioning plate is quickly aligned with the camera lenses, and the protector is accurately adhered to a camera module convex body without generating air bubbles, thereby protecting the camera module convex body from scrapes or direct impacts.