An information transmission method and device, capable of transmitting reference signal and data by using different sub-carrier intervals, are provided. The method includes: a first transmitting end transmits, on a first symbol in a first time-frequency region, a first signal by using a first sub-carrier interval, the first signal being a reference signal; the first transmitting end transmits, on a second symbol in the first time-frequency region, a second signal by using a second sub-carrier interval, the second signal being a data signal or control signal, wherein the first sub-carrier interval is different from the second sub-carrier interval, and the size of the first time-frequency region is the size of the minimum time-frequency scheduling unit of the data signal.