Invention Grant
- Patent Title: ExPEC glycoconjugate vaccine formulations
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Application No.: US16709223Application Date: 2019-12-10
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Publication No.: US11033633B2Publication Date: 2021-06-15
- Inventor: Olga Labovitiadi , Wouter Frank Tonnis , Francesco Doro , Janik Adriaansen
- Applicant: Janssen Pharmaceuticals, Inc.
- Applicant Address: US NJ Titusville
- Assignee: Janssen Pharmaceuticals, Inc.
- Current Assignee: Janssen Pharmaceuticals, Inc.
- Current Assignee Address: US NJ Titusville
- Agency: Ice Miller LLP
- Priority: EP16195256 20161024
- Main IPC: A61K47/64
- IPC: A61K47/64 ; C08B37/00 ; A61K47/65 ; A61K39/108 ; A61K47/02 ; A61K47/20 ; A61K47/26 ; A61K39/00
Abstract:
Compositions and methods for inducing an immune response against extra-intestinal pathogenic Escherichia coli (ExPEC) are described. In particular, multivalent vaccines containing O-antigen polysaccharide covalently bound to an exotoxin A of Pseudomonas aeruginosa (EPA) carrier protein that can withstand multiple environmental stresses are described.
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