A vehicle power unit room structure is provided including a motor that is disposed inside a power unit room and that is configured to transmit drive force to a drive wheel, a compressor that is disposed adjacent to the motor in a vehicle width direction so as to overlap with the motor as viewed along the vehicle width direction, and a power supply section that is configured to supply power supplied from a power source to the motor and the compressor, and that is disposed at a vehicle upper side of the compressor so as to overlap with the compressor as viewed along a vehicle vertical direction.