Invention Grant
![Substituted isoindolin-1-ones and 2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-ones as HPK1 antagonists](/docs/US/2021-06-15/US11034694B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted isoindolin-1-ones and 2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-ones as HPK1 antagonists
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Application No.: US17020122Application Date: 2020-09-14
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Publication No.: US11034694B2Publication Date: 2021-06-15
- Inventor: Neelu Kaila , Ian Linney , Stuart Ward , Grant Wishart , Ben Whittaker , Alexandre Cote , Jeremy Robert Greenwood , Abba Leffler , Steven K. Albanese , Daniel L. Severance
- Applicant: Nimbus Saturn, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Nimbus Saturn, Inc.
- Current Assignee: Nimbus Saturn, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Dechert LLP
- Agent Andrea L. C. Reid; Paul R. Fleming
- Main IPC: A61K31/4035
- IPC: A61K31/4035 ; A61K31/407 ; C07D209/46 ; C07D487/04 ; C07D471/04 ; C07D519/00 ; C07D401/14 ; C07D495/04 ; C07D498/04
![Substituted isoindolin-1-ones and 2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-ones as HPK1 antagonists](/abs-image/US/2021/06/15/US11034694B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides compounds of formula I: or pharmaceutically acceptable salts and/or pharmaceutical compositions thereof. The present invention also provides methods for the inhibition of HPK1 and methods for the treatment of HPK1-mediated disorders.
Public/Granted literature
- US20210078998A1 SUBSTITUTED ISOINDOLIN-1-ONES AND 2,3-DIHYDRO-1H-PYRROLO[3,4-c]PYRIDIN-1-ONES AS HPK1 ANTAGONISTS Public/Granted day:2021-03-18
Information query
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