Invention Grant
- Patent Title: Ethynyl derivatives
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Application No.: US16220512Application Date: 2018-12-14
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Publication No.: US11034699B2Publication Date: 2021-06-15
- Inventor: Barbara Biemans , Wolfgang Guba , Georg Jaeschke , Lothar Lindemann , Fionn O'Hara , Antonio Ricci , Daniel Rueher , Eric Vieira
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Agent Andre T. Krammer
- Priority: EP15176854 20150715
- Main IPC: C07D401/10
- IPC: C07D401/10 ; C07D471/10 ; C07D487/10 ; C07D491/107 ; C07D491/20 ; A61K31/527 ; A61P35/00 ; A61P25/22 ; A61P3/10 ; A61P25/24 ; A61P25/00 ; A61P25/16 ; A61P1/08
Abstract:
The present invention relates to positive allosteric modulators (PAMs) of metabotropic glutamate receptor 4 (mGluR4) that may be used for the treatment of conditions such as Parkinson's disease, anxiety, emesis, obsessive compulsive disorder, autism, neuroprotection, cancer, depression and diabetes type 2.
Public/Granted literature
- US20190119290A1 ETHYNYL DERIVATIVES Public/Granted day:2019-04-25
Information query
