Invention Grant
- Patent Title: Process and new intermediates for the preparation of 11-methylene steroids
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Application No.: US16081835Application Date: 2017-03-02
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Publication No.: US11034716B2Publication Date: 2021-06-15
- Inventor: Celso Miguel Sandoval Rodríguez , Ignacio Herráiz Sierra , Ivano Messina , Jesús Miguel Iglesias Retuerto
- Applicant: Crystal Pharma SA
- Applicant Address: ES Boecillo-Valladolid
- Assignee: Crystal Pharma SA
- Current Assignee: Crystal Pharma SA
- Current Assignee Address: ES Boecillo-Valladolid
- Agency: Knobbe, Martens, Olson & Bear LLP
- Priority: EP16382092 20160303
- International Application: PCT/EP2017/054952 WO 20170302
- International Announcement: WO2017/149091 WO 20170908
- Main IPC: C07J1/00
- IPC: C07J1/00 ; C07J11/00 ; C07J21/00 ; C07J33/00 ; C07J43/00 ; C07J51/00
Abstract:
A process for the preparation of 11-methylene steroids from di-keto steroids involves selective olefination of the ketone at position 11 of the di-keto steroids. The resulting 11-methylene steroid products can be used as intermediates in the preparation of the synthetic steroids, Etonogestrel and Desogestrel, as well as other pharmaceutically active agents.
Public/Granted literature
- US20190092807A1 PROCESS AND NEW INTERMEDIATES FOR THE PREPARATION OF 11-METHYLENE STEROIDS Public/Granted day:2019-03-28
Information query
