Invention Grant
- Patent Title: Hybrid peptide, set of hybrid peptides, composition, uses of the hybrid peptide, method for inducing an immune response and kits
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Application No.: US16485035Application Date: 2018-02-09
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Publication No.: US11034735B2Publication Date: 2021-06-15
- Inventor: Ana Marisa Chudzinski-Tavassi , Bárbara Athayde Vaz Galväo da Silva , Kerly Fernanda Mesquita Pasqualoto , Leo Kei Iwai , Rafael Marques Porto
- Applicant: BIOTICK PESQUISA E DESENVOLVIMENTO TECNOLÓGICO LTDA. , FUNDAÇÃO BUTANTAN
- Applicant Address: BR Säo Caetano do Sul-SP; BR Sâo Paulo-SP
- Assignee: BIOTICK PESQUISA E DESENVOLVIMENTO TECNOLÓGICO LTDA.,FUNDAÇÃO BUTANTAN
- Current Assignee: BIOTICK PESQUISA E DESENVOLVIMENTO TECNOLÓGICO LTDA.,FUNDAÇÃO BUTANTAN
- Current Assignee Address: BR Säo Caetano do Sul-SP; BR Sâo Paulo-SP
- Agency: Hovey Williams LLP
- Priority: BR102017002668-0 20170209
- International Application: PCT/BR2018/050024 WO 20180209
- International Announcement: WO2018/145182 WO 20180816
- Main IPC: C07K14/29
- IPC: C07K14/29 ; A61P31/04 ; A61K39/02 ; A61K39/00
Abstract:
The present invention relates to novel hybrid peptides developed from the combination of membrane surface protein peptide fragments present in anaplasmosis microorganisms, and in particular, bacteria of the species Anaplasma marginale. The present invention further relates to hybrid peptide sets, compositions and kits comprising such novel hybrid peptides, their uses and methods of inducing immune response. Each hybrid peptide, according to the present invention, comprises two or more peptide fragments of amino acid sequences as defined in the present invention linked together by means of a spacer element. The combined peptide fragments are protein peptide fragments of MSP1, MSP1a, MSP1b, MSP2, MSP2-HRV, MSP3, OMP7, OMP8, VirB9 and VirB10.
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