Invention Grant
- Patent Title: Single domain binding molecule
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Application No.: US16297544Application Date: 2019-03-08
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Publication No.: US11034756B2Publication Date: 2021-06-15
- Inventor: Caroline Barelle , Mischa Roland Muller , Valarie Calabro , Jack Bikker , John Steven , Lioudmila Tchistiakova , Oleg Kovalenko , Andrea Olland
- Applicant: ELASMOGEN LIMITED
- Applicant Address: GB Aberdeen
- Assignee: ELASMOGEN LIMITED
- Current Assignee: ELASMOGEN LIMITED
- Current Assignee Address: GB Aberdeen
- Agency: Arrigo, Lee, Guttman & Mouta-Bellum LLP
- Main IPC: C07K16/18
- IPC: C07K16/18 ; C07K16/28 ; C07K16/46 ; A61K39/00
Abstract:
The present invention provides a single domain specific binding molecule having the structure FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain.
Public/Granted literature
- US20190194307A1 SINGLE DOMAIN BINDING MOLECULE Public/Granted day:2019-06-27
Information query
