Invention Grant
- Patent Title: Water-soluble polymeric dyes
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Application No.: US16667250Application Date: 2019-10-29
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Publication No.: US11034840B2Publication Date: 2021-06-15
- Inventor: Glenn P. Bartholomew , Yongchao Liang
- Applicant: Becton, Dickinson and Company
- Applicant Address: US NJ Franklin Lakes
- Assignee: Becton, Dickinson and Company
- Current Assignee: Becton, Dickinson and Company
- Current Assignee Address: US NJ Franklin Lakes
- Agency: Bozicevic, Field & Francis LLP
- Agent Bret E. Field
- Main IPC: C09B69/10
- IPC: C09B69/10 ; G01N33/533

Abstract:
Water soluble polymeric dyes and polymeric tandem dyes are provided. The polymeric dyes include a water solvated light harvesting multichromophore having a conjugated segment of aryl or heteroaryl co-monomers including branched non-ionic water soluble groups (WSG) comprising two or more water soluble polymers. In some cases, the branched non-ionic water soluble groups (WSG) of the present disclosure are capable of imparting solubility in water in excess of 50 mg/mL to the multichromophore. The polymeric tandem dyes further include a signaling chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. Also provided are aggregation-resistant labelled specific binding members that include the subject water soluble polymeric dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject polymeric dyes find use are also provided. Systems and kits for practicing the subject methods are also provided.
Public/Granted literature
- US20200062966A1 Water-Soluble Polymeric Dyes Public/Granted day:2020-02-27
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