Invention Grant
- Patent Title: Microorganism expressing mutant AlkB enzyme and use to prepare omega-hydroxy carboxylic acid and/or ester
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Application No.: US16314768Application Date: 2017-07-03
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Publication No.: US11034938B2Publication Date: 2021-06-15
- Inventor: Arne Skerra , Ludwig Kirmair , Steffen Schaffer , Christoph Schorsch , Mirja Wessel , Thomas Haas
- Applicant: EVONIK DEGUSSA GMBH
- Applicant Address: DE Essen
- Assignee: EVONIK DEGUSSA GMBH
- Current Assignee: EVONIK DEGUSSA GMBH
- Current Assignee Address: DE Essen
- Agency: Smith, Gambrell & Russell, LLP
- Priority: EP16177711 20160704
- International Application: PCT/EP2017/066445 WO 20170703
- International Announcement: WO2018/007289 WO 20180111
- Main IPC: C12N9/02
- IPC: C12N9/02 ; C12P7/64

Abstract:
There is provided a microbial cell expressing a mutant AlkB enzyme, the mutant AlkB enzyme comprising at least one point mutation in the wild type sequence of AlkB, wherein the point mutation is at amino acid position V129 and/or T136 of the wild type AlkB enzyme. There is also provided a method for producing omega-hydroxy carboxylic acid and/or ester thereof using this cell.
Public/Granted literature
- US20190153405A1 MUTANT ALKB GENE Public/Granted day:2019-05-23
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