Invention Grant
- Patent Title: Treatment of tumors with miRNA targeting CDK4/CDK6
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Application No.: US16487355Application Date: 2018-02-26
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Publication No.: US11034959B2Publication Date: 2021-06-15
- Inventor: Amriti R. Lulla , Wafik S. El-Deiry
- Applicant: Institute For Cancer Research
- Applicant Address: US PA Philadelphia
- Assignee: Institute For Cancer Research
- Current Assignee: Institute For Cancer Research
- Current Assignee Address: US PA Philadelphia
- Agency: Stradley Ronon Stevens & Young, LLP
- International Application: PCT/US2018/019649 WO 20180226
- International Announcement: WO2018/157026 WO 20180830
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/04 ; C12N15/113 ; A61P35/00 ; A61K45/06
Abstract:
The present disclosure provides miRNA mimics targeting CDK4 and/or CDK6, and compositions comprising the same. Methods for the treatment of tumors, including but not limited to colon cancer, comprising administering a modified oligonucleotide comprising a miRNA are also disclosed herein.
Public/Granted literature
- US20200056184A1 TREATMENT OF TUMORS WITH MIRNA TARGETING CDK4/CDK6 Public/Granted day:2020-02-20
Information query
