Invention Grant
- Patent Title: Biomarkers for cancer
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Application No.: US15742702Application Date: 2016-07-08
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Publication No.: US11035008B2Publication Date: 2021-06-15
- Inventor: Monica Hellesoy , Linn Hodneland Nilsson , David Robert Micklem
- Applicant: BERGENBIO ASA
- Applicant Address: NO Bergen
- Assignee: BERGENBIO ASA
- Current Assignee: BERGENBIO ASA
- Current Assignee Address: NO Bergen
- Agency: McNeill Baur PLLC
- Priority: GB1512133 20150710
- International Application: PCT/EP2016/066357 WO 20160708
- International Announcement: WO2017/009261 WO 20170119
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886
Abstract:
The use of PHGDH as a biomarker for detecting the occurrence of epithelial-to-mesenchymal transition (EMT) in a subject, and the use of PHGDH modulators to treat cancer is disclosed herein. Also disclosed are various methods for detecting the occurrence of epithelial-to-mesenchymal transition (EMT) in a subject by measuring PHGDH expression and/or activity.
Public/Granted literature
- US20180208989A1 BIOMARKERS FOR CANCER Public/Granted day:2018-07-26
Information query
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