Invention Grant
- Patent Title: Identifying drug candidates for treating polycystic kidney disease using organoids generated from primary cells
-
Application No.: US16003293Application Date: 2018-06-08
-
Publication No.: US11035852B2Publication Date: 2021-06-15
- Inventor: Jeffrey Matthijn Beekman , Johanna Florentia Dekkers , Cornelis Korstiaan Van Der Ent , Johannes C. Clevers
- Applicant: UMC Utrecht Holding B.V. , Koninklijke Nederlandse Akademie van Wetenschappen
- Applicant Address: NL CM Utrecht; NL CT Utrecht
- Assignee: UMC Utrecht Holding B.V.,Koninklijke Nederlandse Akademie van Wetenschappen
- Current Assignee: UMC Utrecht Holding B.V.,Koninklijke Nederlandse Akademie van Wetenschappen
- Current Assignee Address: NL CM Utrecht; NL CT Utrecht
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: G01N33/50
- IPC: G01N33/50
Abstract:
The invention relates to an assay for diagnosing a disease or affliction that affects fluid uptake or secretion or for studying the effectiveness of one or more drugs for treating the disease or affliction, wherein the assay comprises measuring swelling of one or more organoids.
Public/Granted literature
- US20190383799A1 RAPID QUANTITATIVE ASSAY TO MEASURE CFTR FUNCTION IN A PRIMARY INTESTINAL CULTURE MODEL Public/Granted day:2019-12-19
Information query
IPC分类:
