An ultrasound scanning system includes a probe adaptor, a plurality of channel modules and a backend controller. The probe adaptor is connected to an ultrasound probe and has a plurality of frontend channels. Each of the channel modules has an identification code and includes a switch, a transmitter, a transmitter beamformer, a receiver and a receiver beamformer, wherein the switch is coupled to the probe adaptor, the transmitter is coupled to the switch, the transmitter beamformer is coupled to the transmitter, the receiver is coupled to the switch, and the receiver beamformer is coupled to the receiver. The backend controller is coupled to the probe adaptor, the transmitter beamformer of each of the channel modules and the receiver beamformer of each of the channel modules.