A color filter substrate and a liquid crystal display panel are provided. The color filter substrate includes photoresist blocks spaced apart, a black matrix disposed between adjacent photoresist blocks, an optically thinner medium film disposed on the photoresist blocks and the black matrix, and an overcoat layer covering the photoresist blocks, the black matrix, and the optically thinner medium film. The optically thinner medium film covers a boundary between the photoresist blocks and the black matrix. A refractive index of the optically thinner medium film is less than that of the overcoat layer. The color filter substrate and a TFT array substrate are formed into the liquid crystal display panel. Light is totally reflected at an interface between the overcoat layer and the optically thinner medium film, thereby solving issues of color shifts at large viewing angles without affecting transmittance of the liquid crystal display panel.