Calibration and distance prediction for driving assistance is provided. A camera of a vehicle is calibrated to obtain a distance data set. The distance data set includes a distance of each row of pixels of a first image captured by the camera. The distance data set may be further utilized in real-time to predict a distance of an object from the vehicle. Based on the predicted distance, a warning message for an impending collision may be generated and communicated to a driver of the vehicle, thereby facilitating driving assistance to the driver in the real-time.