Invention Grant
- Patent Title: Prodrugs of nucleoside phosphonates
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Application No.: US16495606Application Date: 2018-03-21
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Publication No.: US11040047B2Publication Date: 2021-06-22
- Inventor: Graciela Andrei , Steven De Jonghe , Elisabetta Groaz , Piet Herdewijn , Min Luo , Dominique Schols , Robert Snoeck
- Applicant: Katholieke Universiteit Leuven
- Applicant Address: BE Leuven
- Assignee: Katholieke Universiteit Leuven
- Current Assignee: Katholieke Universiteit Leuven
- Current Assignee Address: BE Leuven
- Agency: Knobbe Martens Olson & Bear LLP
- Priority: GB1704577 20170323,GB1711193 20170712
- International Application: PCT/EP2018/057180 WO 20180321
- International Announcement: WO2018/172416 WO 20180927
- Main IPC: A61K31/675
- IPC: A61K31/675 ; A61P31/22 ; C07F9/6584
Abstract:
The present invention relates to novel phosphonoamidate prodrugs. The invention also relates to the use of these novel phosphonate-modified nucleosides to treat or prevent viral infections and their use to manufacture a medicine to treat or prevent viral infections, particularly infections with viruses such as the herpes simplex virus 1, herpes simplex virus 2, human cytomegalovirus, varicella zoster virus, vaccinia virus and adenovirus.
Public/Granted literature
- US20200016180A1 NOVEL PRODRUGS OF NUCLEOSIDE PHOSPHONATES Public/Granted day:2020-01-16
Information query
