Invention Grant
- Patent Title: Amide derivative
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Application No.: US15121687Application Date: 2015-02-27
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Publication No.: US11040937B2Publication Date: 2021-06-22
- Inventor: Haruhisa Kikuchi , Yoshiteru Oshima , Toshio Hattori , Yuzuru Kubohara , Osamu Yamada , Jing Zhang , Yoshihisa Matsushita , Shinya Kida
- Applicant: TOHOKU UNIVERSITY , NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY , FUSO PHARMACEUTICAL INDUSTRIES, LTD.
- Applicant Address: JP Sendai; JP Maebashi; JP Osaka
- Assignee: TOHOKU UNIVERSITY,NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY,FUSO PHARMACEUTICAL INDUSTRIES, LTD.
- Current Assignee: TOHOKU UNIVERSITY,NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY,FUSO PHARMACEUTICAL INDUSTRIES, LTD.
- Current Assignee Address: JP Sendai; JP Maebashi; JP Osaka
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: JPJP2014-038919 20140228
- International Application: PCT/JP2015/055873 WO 20150227
- International Announcement: WO2015/129860 WO 20150903
- Main IPC: C07C235/50
- IPC: C07C235/50 ; C07C235/48 ; C07C233/36 ; C07C233/78 ; C07C233/62 ; C07D309/08 ; C07D471/04 ; C07D213/81 ; C07C235/60 ; C07C237/22 ; C07C237/42 ; C07D209/14 ; C07C237/34 ; A61K31/437 ; A61K31/4045 ; A61K31/4409 ; A61K31/445 ; A61K31/40 ; A61K31/351 ; A61K31/167 ; A61K31/381 ; A61K31/397 ; A61K31/166 ; A61K31/165 ; C07D205/04 ; C07D207/16 ; C07D211/60 ; C07D333/38

Abstract:
The present invention provides a useful medicament for the treatment and/or prophylaxis of a disease associated with the enhancement of OPN production including cancer, which comprises a compound of formula: wherein R1, R2, R3, R4, R5, R6, R7, m, n, p, X, and Y are as defined in the specification, a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20160368860A1 AMIDE DERIVATIVE Public/Granted day:2016-12-22
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