Invention Grant
- Patent Title: Methods for detecting autoantibodies against a GABA(A) receptor alpha 1 subunit and/or beta 3 subunit in autoimmune seizure and/or encephalitis
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Application No.: US15023131Application Date: 2014-10-16
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Publication No.: US11041005B2Publication Date: 2021-06-22
- Inventor: Josep Dalmau
- Applicant: INSTITUT D'INVESTIGACIONES BIOMÈDIQUES AUGUST PI I SUNYER , INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANCATS
- Applicant Address: ES Barcelona; ES Barcelona
- Assignee: INSTITUT D'INVESTIGACIONES BIOMÈDIQUES AUGUST PI I SUNYER,INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANCATS
- Current Assignee: INSTITUT D'INVESTIGACIONES BIOMÈDIQUES AUGUST PI I SUNYER,INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANCATS
- Current Assignee Address: ES Barcelona; ES Barcelona
- Agency: Grüneberg and Myers PLLC
- Priority: EP13189172 20131017
- International Application: PCT/EP2014/072252 WO 20141016
- International Announcement: WO2015/055776 WO 20150423
- Main IPC: A61K38/00
- IPC: A61K38/00 ; G01N33/564 ; C07K14/47 ; G01N33/94
Abstract:
The present invention provides a use of a GABA(A)R, GABA(A)R fragment, or homolog thereof or a cell expressing the GABA(A)R, GABA(A)R fragment, or homolog thereof for the prognosis, diagnosis or treatment of an autoimmune disease in a subject, methods of prognosticating, diagnosing or treating an autoimmune disease, an autoantibody binding to a GABA(A)R, GABA(A)R fragment, or homolog thereof, a method for isolating an antibody binding to a GABA(A)R, GABA(A)R fragment, or homolog thereof, and a test kit, pharmaceutical composition and medical or diagnostic device comprising a GABA(A)R, GABA(A)R fragment, or homolog thereof.
Public/Granted literature
- US20160326227A1 DIAGNOSTIC METHOD FOR DETECTING A GABA(A) RELATED AUTOIMMUNE DISEASE AND RELATED SUBJECT-MATTER Public/Granted day:2016-11-10
Information query
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