Invention Grant
- Patent Title: Universal immune receptor expressed by T cells for the targeting of diverse and multiple antigens
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Application No.: US16298310Application Date: 2019-03-11
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Publication No.: US11041012B2Publication Date: 2021-06-22
- Inventor: Nathalie Scholler , Katarzyna Urbanska , Daniel J. Powell
- Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Applicant Address: US PA Philadelphia
- Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Current Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Current Assignee Address: US PA Philadelphia
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Kathryn Doyle
- Main IPC: C07K14/725
- IPC: C07K14/725 ; C07K14/705 ; C07K14/465 ; C12N15/85 ; A61K47/68
Abstract:
The invention provides compositions and methods for adoptive T cell therapy in treating a variety of disorders including cancer, infections, and autoimmune disorders. In one embodiment, the invention provides a universal immune receptor (UnivIR) that comprises an extracellular label binding domain, a transmembrane domain, and a cytoplasmic domain or otherwise an intracellular domain.
Public/Granted literature
- US20190330300A1 Universal Immune Receptor Expressed by T Cells for the Targeting of Diverse and Multiple Antigens Public/Granted day:2019-10-31
Information query
