- Patent Title: Method for predicting a subject's response to valproic acid therapy
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Application No.: US15977144Application Date: 2018-05-11
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Publication No.: US11041207B2Publication Date: 2021-06-22
- Inventor: Catherine L. Clelland , James D. Clelland
- Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK , RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC.
- Applicant Address: US NY New York; US NY Menands
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK,RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC.
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK,RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC.
- Current Assignee Address: US NY New York; US NY Menands
- Agency: Bryan Cave Leighton Paisner LLP
- Main IPC: C12Q1/6883
- IPC: C12Q1/6883 ; A61K31/19 ; A61K31/198 ; A61P25/18 ; G01N33/68
Abstract:
The present invention provides, inter alia, methods for treating or ameliorating the effects of a disorder, such as schizophrenia or bipolar disorder, by increasing or decreasing proline levels. Further provided are methods of predicting and monitoring the clinical response in a patient, and diagnostic systems for identifying a patient likely to benefit from proline modulation.
Public/Granted literature
- US20180275149A1 METHOD FOR PREDICTING A SUBJECT'S RESPONSE TO VALPROIC ACID THERAPY Public/Granted day:2018-09-27
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