A multi-coupling system includes a first multi-coupling component including a plurality of individual first fluid couplers, and a second multi-coupling component including a plurality of individual second fluid couplers. The second multi-coupling component includes a locking pin assembly that is attached to a handle assembly, the locking pin assembly including a locking pin that is moveable in an axial direction between an extended position and a retracted position; a housing that houses the plurality of individual second fluid couplers, the housing further including a locking pin hole; and an operating lever configured to manipulate the locking pin assembly. In a connected and locked state, the locking pin is in the extended position in which a shaft end of the locking pin is located in the locking pin hole, thereby preventing rotation of the handle assembly. The locking pin assembly is manipulated by a user operation of the operating lever to move the locking pin from the extended position to the retracted position out from the locking pin hole to configure the multi-coupling system in a connected and unlocked state in which the handle assembly is rotatable to reconfigure the multi-coupling system to the disconnected state.